Evaluation of two commercial human T-cell lymphotropic virus western blot (immunoblot) kits with problem specimens.

Evaluation of two commercial human T-cell lymphotropic virus western blot (immunoblot) kits with problem specimens.

We evaluated two commercial human T-cell lymphotropic virus (HTLV) Western blot (WB; immunoblot) kits, Cambridge Biotech Corp. (CBC) and Diagnostic Biotechnology Ltd. (DBL). Both strategies make use of HTLV sort I (HTLV-I) viral lysate and rgp21. The DBL WB package additionally distinguishes between HTLV-I and HTLV-II antibodies, utilizing an HTLV-I-specific and an HTLV-II-specific recombinant. Fifty weakly reactive HTLV-II-positive plasma specimens which … Read more

Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests.

Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests.

Rapid diagnostic assessments (RDTs) play an important function in the administration and management of malaria an infection. The histidine-rich protein 2 (PfHRP-2) based mostly RDTs are the mostly used RDTs for malaria analysis in Sudan. Deletion of pfhrp2 in Plasmodium falciparum genome have an effect on the accuracy of PfHRP-2 based mostly RDT kits. This examine … Read more

Repeat HIV testing of individuals with discrepant HIV self-test results in Central Uganda.

Repeat HIV testing of individuals with discrepant HIV self-test results in Central Uganda.

According to the person directions from the producer of OraQuick HIV self-test (HIVST) kits, individuals whose kits present one purple band ought to be thought of to be HIV-negative, regardless of how weak the band is. However, latest studies present potential for a second false weak band after storage, thereby creating confusion in the interpretation of results. In … Read more